منابع مشابه
Thrombocytopenia and platelet transfusion
Thrombocytopenia is caused by disorders impairing platelet production, causing platelet destruction or leading to platelet sequestration. In addition, there are both congenital and acquired disorders of platelet function. These latter conditions may lead to the functional equivalent of thrombocytopenia, often despite the presence of a normal platelet count. Platelet transfusion represents an im...
متن کاملSingle donor platelet transfusion.
Cytopheresis equipment from a number of manufacturers now permits the rapid, safe, and efficient procurement of functionally normal platelets from single donors. There has been an extensive proliferation of these blood cell separators and virtually all large blood collection centers and most large hospitals have at least one blood cell separator in operation. Transfusions from single donors sel...
متن کاملBlood platelet kinetics and platelet transfusion.
The discovery of citrate anticoagulant in the 1920s and the development of plastic packs for blood collection in the 1960s laid the groundwork for platelet transfusion therapy on a scale not previously possible. A major limitation, however, was the finding that platelet concentrates prepared from blood anticoagulated with citrate were unsuitable for transfusion because of platelet clumping. We ...
متن کاملTRANSFUSION MEDICINE Factors affecting posttransfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patients
A variety of patientand product-related factors influenced the outcome of 6379 transfusions given to 533 patients in the Trial to Reduce Alloimmunization to Platelets (TRAP). Responses measured were platelet increments, interval between platelet transfusions, and platelet refractoriness. Patient factors that improved platelet responses were splenectomy and increasing patient age. In contrast, a...
متن کاملTransfusion Medicine 2 Platelet transfusions
Ever since platelet transfusions were shown to reduce mortality from haemorrhage in patients with acute leukaemia in the 1950s, the use of this therapy has steadily grown to become an essential part of the treatment of cancer, haematological malignancies, marrow failure, and haematopoietic stem cell transplantation. Today, more than 1·5 million platelet products are transfused in the USA each y...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the Japan Society of Blood Transfusion
سال: 1997
ISSN: 1883-8383,0546-1448
DOI: 10.3925/jjtc1958.43.23